Potent, non-competitive mGluR1 antagonist (Ki=-0.34 nM). Inhibits glutamate-induced Ca2+ response at the human mGluR1 (IC50=0.55 nM). Selective over mGluR5 (>400-fold).
| A.G. Scientific, Inc. | |
|---|---|
| Product Category | Biological Materials |
| Product Number | J-1100 |
| Product Name | JNJ 16259685 |