Cell-permeable. Maintains the undifferentiated state of embrryonic stem cells. By targeting the PR72/130 subunit of the Ser/Thr phosphatases PP2A, it prevents β -catenin from switching coactivator usage from CBP to p300. The increase in β -cateinin/CBP mediated transcription at the expense of β-cateinin/CBP mediated transcription helps to maintain the murine stem cell pluripotency.
| A.G. Scientific, Inc. | |
|---|---|
| Product Category | Biological Materials |
| Product Number | I-1332 |
| Product Name | IQ-1 |
