IM-54 is an indolylmaleimide derivative which, at 1 μM, inhibits necrotic cell death induced by H2O2 in promyelocytic leukemia HL-60 cells. It does not prevent etoposide-induced apoptosis and does not inhibit protein kinase C or S6 kinase 1.
K. Dodo, et al.; Bioorg. Med. Chem. LEtt. 15, 3114 (2005).
| A.G. Scientific, Inc. | |
|---|---|
| Product Category | Biological Materials |
| Product Number | I-1322 |
| Product Name | IM-54 |