A.G. Scientific, Inc. GSK-2126458 G-2340

Description
Cell-permeable. A highly potent, pan phosphoinositide 3-kinase (PI 3-K) family kinase inhibitor with biochemical Ki's of 0.019 nM (PI 3-Kâº), 0.13 nM (PI 3-Kβ), 0.024 nM (PI 3-Kî´), 0.06 nM (PI 3-Ké£), 0.18 nM (mTORC1), and 0.3 nM (mTORC2). In vivo, GSK2126458 displays anti-tumor activity in both pharmacodynamic and tumor growth efficacy models.
Description
Cell-permeable. A highly potent, pan phosphoinositide 3-kinase (PI 3-K) family kinase inhibitor with biochemical Ki's of 0.019 nM (PI 3-Kâº), 0.13 nM (PI 3-Kβ), 0.024 nM (PI 3-Kî´), 0.06 nM (PI 3-Ké£), 0.18 nM (mTORC1), and 0.3 nM (mTORC2). In vivo, GSK2126458 displays anti-tumor activity in both pharmacodynamic and tumor growth efficacy models.

Suppliers

Company
Product
Description
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A.G. Scientific, Inc.
San Diego, CA, USA
GSK-2126458
G-2340
GSK-2126458 G-2340
Cell-permeable. A highly potent, pan phosphoinositide 3-kinase (PI 3-K) family kinase inhibitor with biochemical Ki's of 0.019 nM (PI 3-Kâº), 0.13 nM (PI 3-Kβ), 0.024 nM (PI 3-Kî´), 0.06 nM (PI 3-Ké£), 0.18 nM (mTORC1), and 0.3 nM (mTORC2). In vivo, GSK2126458 displays anti-tumor activity in both pharmacodynamic and tumor growth efficacy models.

Cell-permeable. A highly potent, pan phosphoinositide 3-kinase (PI 3-K) family kinase inhibitor with biochemical Ki's of 0.019 nM (PI 3-Kâº), 0.13 nM (PI 3-Kβ), 0.024 nM (PI 3-Kδ), 0.06 nM (PI 3-KÉ£), 0.18 nM (mTORC1), and 0.3 nM (mTORC2). In vivo, GSK2126458 displays anti-tumor activity in both pharmacodynamic and tumor growth efficacy models.

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Technical Specifications

  A.G. Scientific, Inc.
Product Category Biological Materials
Product Number G-2340
Product Name GSK-2126458
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