A.G. Scientific, Inc. GDC-0449, Vismodegib G-2334

Description
GDC-0449, Vismodegib is a potent inhibitor of Smoothened (SMO), a key mediator of Hedgehog (Hh) signaling pathway. GDC-0449, Vismodegib inhibition of SMO renders the transcription factor GLI inactive, thus preventing the expression of genes that mediate the role of Hh on tumor growth.
Description
GDC-0449, Vismodegib is a potent inhibitor of Smoothened (SMO), a key mediator of Hedgehog (Hh) signaling pathway. GDC-0449, Vismodegib inhibition of SMO renders the transcription factor GLI inactive, thus preventing the expression of genes that mediate the role of Hh on tumor growth.

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Product
Description
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A.G. Scientific, Inc.
San Diego, CA, USA
GDC-0449, Vismodegib
G-2334
GDC-0449, Vismodegib G-2334
GDC-0449, Vismodegib is a potent inhibitor of Smoothened (SMO), a key mediator of Hedgehog (Hh) signaling pathway. GDC-0449, Vismodegib inhibition of SMO renders the transcription factor GLI inactive, thus preventing the expression of genes that mediate the role of Hh on tumor growth.

GDC-0449, Vismodegib is a potent inhibitor of Smoothened (SMO), a key mediator of Hedgehog (Hh) signaling pathway. GDC-0449, Vismodegib inhibition of SMO renders the transcription factor GLI inactive, thus preventing the expression of genes that mediate the role of Hh on tumor growth.

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Technical Specifications

  A.G. Scientific, Inc.
Product Category Biological Materials
Product Number G-2334
Product Name GDC-0449, Vismodegib
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