A.G. Scientific, Inc. GM6001 G-1231

Description
GM6001, GM-6001 is a potent, cell-permeable, broad-spectrum hydroxamic acid inhibitor of matrix metalloproteinases (MMPs); (Ki = 400 pM for MMP-1; Ki = 500 pM for MMP-2; Ki = 27 nM for MMP-3; Ki = 100 pM for MMP-8; and Ki = 200 pM for MMP-9). GM-6001 prevents the release of TNF-a in vivo and in vitro and abrogates endotoxin-induced lethality in mice.
Description
GM6001, GM-6001 is a potent, cell-permeable, broad-spectrum hydroxamic acid inhibitor of matrix metalloproteinases (MMPs); (Ki = 400 pM for MMP-1; Ki = 500 pM for MMP-2; Ki = 27 nM for MMP-3; Ki = 100 pM for MMP-8; and Ki = 200 pM for MMP-9). GM-6001 prevents the release of TNF-a in vivo and in vitro and abrogates endotoxin-induced lethality in mice.

Suppliers

Company
Product
Description
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A.G. Scientific, Inc.
San Diego, CA, USA
GM6001
G-1231
GM6001 G-1231
GM6001, GM-6001 is a potent, cell-permeable, broad-spectrum hydroxamic acid inhibitor of matrix metalloproteinases (MMPs); (Ki = 400 pM for MMP-1; Ki = 500 pM for MMP-2; Ki = 27 nM for MMP-3; Ki = 100 pM for MMP-8; and Ki = 200 pM for MMP-9). GM-6001 prevents the release of TNF-a in vivo and in vitro and abrogates endotoxin-induced lethality in mice.

GM6001, GM-6001 is a potent, cell-permeable, broad-spectrum hydroxamic acid inhibitor of matrix metalloproteinases (MMPs); (Ki = 400 pM for MMP-1; Ki = 500 pM for MMP-2; Ki = 27 nM for MMP-3; Ki = 100 pM for MMP-8; and Ki = 200 pM for MMP-9).
GM-6001 prevents the release of TNF-a in vivo and in vitro and abrogates endotoxin-induced lethality in mice.

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Technical Specifications

  A.G. Scientific, Inc.
Product Category Biological Materials
Product Number G-1231
Product Name GM6001
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