A.G. Scientific, Inc. DAPT D-1210

Description
Cell permeable inhibitor of î³-secretase (IC50=115 nM for total β-amyloid, IC50=200 nM for β-amyloid 1-42). Does not inhibit presenilinase. Antagonizes Notch signaling through inhibition of Notch processing. DAPT treatment can influence hematopoietic cell fate decisions and enhances neuronal differentiation in embryonic stel cell-derived embryoid bodies independent of sonic hedgehog (Shh) signaling.
Description
Cell permeable inhibitor of î³-secretase (IC50=115 nM for total β-amyloid, IC50=200 nM for β-amyloid 1-42). Does not inhibit presenilinase. Antagonizes Notch signaling through inhibition of Notch processing. DAPT treatment can influence hematopoietic cell fate decisions and enhances neuronal differentiation in embryonic stel cell-derived embryoid bodies independent of sonic hedgehog (Shh) signaling.

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Company
Product
Description
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A.G. Scientific, Inc.
San Diego, CA, USA
DAPT
D-1210
DAPT D-1210
Cell permeable inhibitor of î³-secretase (IC50=115 nM for total β-amyloid, IC50=200 nM for β-amyloid 1-42). Does not inhibit presenilinase. Antagonizes Notch signaling through inhibition of Notch processing. DAPT treatment can influence hematopoietic cell fate decisions and enhances neuronal differentiation in embryonic stel cell-derived embryoid bodies independent of sonic hedgehog (Shh) signaling.

Cell permeable inhibitor of γ-secretase (IC50=115 nM for total β-amyloid, IC50=200 nM for β-amyloid 1-42). Does not inhibit presenilinase. Antagonizes Notch signaling through inhibition of Notch processing. DAPT treatment can influence hematopoietic cell fate decisions and enhances neuronal differentiation in embryonic stel cell-derived embryoid bodies independent of sonic hedgehog (Shh) signaling.

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Technical Specifications

  A.G. Scientific, Inc.
Product Category Biological Materials
Product Number D-1210
Product Name DAPT
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