A potent and highly selective inhibitor of glycerine synthase kinase-3β (GSK-2β) (IC50 =6.7 nM). CHIR99021 has been shown to allow for long-term expansion of murine embryonic stem cells in a chemically-defined medium in conjunction with MEK/MAPK inhibitor PD184352 and fibroblast growth factor receptor (FGFR) inhibitor SU5402.
| A.G. Scientific, Inc. | |
|---|---|
| Product Category | Biological Materials |
| Product Number | C-1702 |
| Product Name | CHIR99021 |
