A.G. Scientific, Inc. Beta-Secretase Inhibitor II B-2430

Description
A potent, cell permeable and reversible inhibitor of β-secretase that corresponds to the β-secretase cleavage site (VNL-DA) of the Swedish mutant Amyloid Precursor Protein (APP). Inhibits the formation of both Aβtotal (IC50 = 700 nM) and Aβ1-42 (IC50 = 2.5 μM) in CHO cells stably transfected with wild-type APP751.
Description
A potent, cell permeable and reversible inhibitor of β-secretase that corresponds to the β-secretase cleavage site (VNL-DA) of the Swedish mutant Amyloid Precursor Protein (APP). Inhibits the formation of both Aβtotal (IC50 = 700 nM) and Aβ1-42 (IC50 = 2.5 μM) in CHO cells stably transfected with wild-type APP751.

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A.G. Scientific, Inc.
San Diego, CA, USA
Beta-Secretase Inhibitor II
B-2430
Beta-Secretase Inhibitor II B-2430
A potent, cell permeable and reversible inhibitor of β-secretase that corresponds to the β-secretase cleavage site (VNL-DA) of the Swedish mutant Amyloid Precursor Protein (APP). Inhibits the formation of both Aβtotal (IC50 = 700 nM) and Aβ1-42 (IC50 = 2.5 μM) in CHO cells stably transfected with wild-type APP751.

A potent, cell permeable and reversible inhibitor of β-secretase that corresponds to the β-secretase cleavage site (VNL-DA) of the Swedish mutant Amyloid Precursor Protein (APP). Inhibits the formation of both Aβtotal (IC50 = 700 nM) and Aβ1-42 (IC50 = 2.5 μM) in CHO cells stably transfected with wild-type APP751.

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Technical Specifications

  A.G. Scientific, Inc.
Product Category Biological Materials
Product Number B-2430
Product Name Beta-Secretase Inhibitor II
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