A.G. Scientific, Inc. AMI-1 A-2184

Description
Cell-permeable. A potent and specific protein arginine N-methyltransferase (PRMTs) inhibitor (IC50 = 8.8 μM for human PRMT1 and 3.0 μM for yeast Hmt1p ). Does not compete for the AdoMet (S-adenosyl-L-methio nine; SAM) binding site. Also acts as a HIV-1 RT polymerase inhibitor (IC50 = 5.0 μM).
Description
Cell-permeable. A potent and specific protein arginine N-methyltransferase (PRMTs) inhibitor (IC50 = 8.8 μM for human PRMT1 and 3.0 μM for yeast Hmt1p ). Does not compete for the AdoMet (S-adenosyl-L-methio nine; SAM) binding site. Also acts as a HIV-1 RT polymerase inhibitor (IC50 = 5.0 μM).

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Company
Product
Description
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A.G. Scientific, Inc.
San Diego, CA, USA
AMI-1
A-2184
AMI-1 A-2184
Cell-permeable. A potent and specific protein arginine N-methyltransferase (PRMTs) inhibitor (IC50 = 8.8 μM for human PRMT1 and 3.0 μM for yeast Hmt1p ). Does not compete for the AdoMet (S-adenosyl-L-methio nine; SAM) binding site. Also acts as a HIV-1 RT polymerase inhibitor (IC50 = 5.0 μM).

Cell-permeable. A potent and specific protein arginine N-methyltransferase (PRMTs) inhibitor (IC50 = 8.8 μM for human PRMT1 and 3.0 μM for yeast Hmt1p ). Does not compete for the AdoMet (S-adenosyl-L-methionine; SAM) binding site. Also acts as a HIV-1 RT polymerase inhibitor (IC50 = 5.0 μM).

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Technical Specifications

  A.G. Scientific, Inc.
Product Category Biological Materials
Product Number A-2184
Product Name AMI-1
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