A.G. Scientific, Inc. Amidepsine D A-1450

Description
Inhibitor of diacylglycerol acyltransferase (DGAT). Shows inhibitory effect in rat liver microsomes (IC50=17.5 μM) and Raji cells (IC50=2.8 μM). Excessive accumulation of triacetylglycerol produced by DGAT may cause fatty liver, obesity and hypertriglyceridemia , which may lead to atherosclerosis, diabetes and metabolic disorders.
Description
Inhibitor of diacylglycerol acyltransferase (DGAT). Shows inhibitory effect in rat liver microsomes (IC50=17.5 μM) and Raji cells (IC50=2.8 μM). Excessive accumulation of triacetylglycerol produced by DGAT may cause fatty liver, obesity and hypertriglyceridemia , which may lead to atherosclerosis, diabetes and metabolic disorders.

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Product
Description
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A.G. Scientific, Inc.
San Diego, CA, USA
Amidepsine D
A-1450
Amidepsine D A-1450
Inhibitor of diacylglycerol acyltransferase (DGAT). Shows inhibitory effect in rat liver microsomes (IC50=17.5 μM) and Raji cells (IC50=2.8 μM). Excessive accumulation of triacetylglycerol produced by DGAT may cause fatty liver, obesity and hypertriglyceridemia , which may lead to atherosclerosis, diabetes and metabolic disorders.

Inhibitor of diacylglycerol acyltransferase (DGAT). Shows inhibitory effect in rat liver microsomes (IC50=17.5 μM) and Raji cells (IC50=2.8 μM). Excessive accumulation of triacetylglycerol produced by DGAT may cause fatty liver, obesity and hypertriglyceridemia, which may lead to atherosclerosis, diabetes and metabolic disorders.

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Technical Specifications

  A.G. Scientific, Inc.
Product Category Biological Materials
Product Number A-1450
Product Name Amidepsine D
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