Park Systems, Inc. XE-Bio

XE-Bio is a powerful 3-in-1 nanoscience research tool that uniquely combines industry’s only True Non-Contact AFM with Ion Conductance Microscopy (ICM) and inverted optical microscope on the same platform. The modular design of the XE-Bio allows easy exchange between non-contact AFM and ICM. Designed for non-invasive in-liquid imaging, the combined imaging capability of AFM, ICM, and inverted optical microscopy makes the XE-Bio ideal for imaging biological samples, such as living cells, in dynamic conditions. Moreover, ICM can be adapted to enable a host of powerful applications in nanoscale electrophysiology. Powerful 3-in-1 Nanoscale Research Tool with Modular Platform • True Non-Contact Atomic Force Microscope (AFM) • Ion Conductance Microscope (ICM) • Inverted Optical Microscope Ultimate AFM Resolution by True Non-Contact Mode • 10 times larger Z-scan bandwidth than a piezotube • Less tip wear for prolonged high-quality and high-resolution imaging • Minimized sample damage or modification • Immunity from parameter-dependent results observed in tapping imaging • Single molecule Force-Distance spectroscopy with automated data analysis Non-invasive In-liquid Imaging by ICM • Monitoring ion channels of single living cells • Unique functional capability of targeted localized stimulation • Enable nanoscale patch-clamping for electrophysiology • Environmental chamber for temperature, pH, and humidity control Fully Integrated Inverted Optical Microscope • Compatible with phase contrast and DIC imaging • Also compatible with fluorescence microscopy • Advanced image overlay functions