Description
Additional Properties
Hydrolytic Sensitivity 4: no reaction with water under neutral conditions Application Forms polymers with very high oxygen permeability.1 Polymerization catalyzed with TaCl5/(C6H5)3Bi.2 Converts aldehydes to 1,3-dienes in presence of Cp2Zr(H)Cl.3 Synthetic reagent.4 Used in the preparation of alkynylxenon fluoride.5 Useful in silicon-mediated Sonogashira cross-coupling reactions.6 Reference 1. Masuda, T. et al. J. Am. Chem. Soc. 1983, 105, 7473. 2. Masuda, T. et al. J. Polym. Sci., Part A: Polym. Chem. 1987, 25, 1353. 3. Maeta, H. et al. Tetrahedron Lett. 1992, 33, 5969. 4. F&F: Vol. 2, p 239; Vol. 6, p 638. 5. Schmidt, H. et al. Inorg. Chem. 2004, 43, 1837. 6. Larson, G. L. “Silicon-Based Cross-Coupling Reagents” Gelest, Inc. 2011. Safety
Packaging Under Nitrogen Alkynylsilane Cross-Coupling Agent The cross-coupling reaction is a highly useful methodology for the formation of carbon-carbon bonds. It involves two reagents, with one typically being a suitable organometallic reagent - the nucleophile - and the other a suitable organic substrate, normally an unsaturated halide, tosylate or similar - the electrophile. 1-Trimethylsilylprop
yne; Propynyltrimethylsil
ane; 1-(Trimethylsilyl)pr
op-1-yne
Forms polymers with very high oxygen permeability
Useful in Sonogashira reactions
Polymerization catalyzed with TaCl5/(C6H5)3Bi
Converts aldehydes to 1,3-dienes in presence of Cp2Zr(H)Cl
Used in the preparation of alkynylxenon fluoride
Polymeric version available, SSP-070
Extensive review of silicon based cross-coupling agents: Denmark, S. E. et al. "Organic Reactions, Volume 75" Denmark, S. E. ed., John Wiley and Sons, 233, 2011
