Gelest, Inc. 3-TRIMETHYLSILYLPROPYNAL SIT8606.3

Additional Properties Hydrolytic Sensitivity 4: no reaction with water under neutral conditions Application Used in the preparation of 1,3,5-triynes.1 Reference 1. Mukai, C. et al. J. Org. Chem. 2001, 66, 5875. Safety Packaging Under Nitrogen Alkynylsilane Cross-Coupling Agent The cross-coupling reaction is a highly useful methodology for the formation of carbon-carbon bonds. It involves two reagents, with one typically being a suitable organometallic reagent - the nucleophile - and the other a suitable organic substrate, normally an unsaturated halide, tosylate or similar - the electrophile. 3-Trimethylsilylprop ynal; 3-Trimethylsilyl-2-p ropyn-1-al; 3-(Trimethylsilyl)pr opargyl aldehyde; Trimethylsilyl)acety lenecarboxaldehyde Potential for the formation of alkynyl aldehydes Used in the preparation of 1,3,5-triynes Potential for the synthesis of 3-subsubstituted alkynals Extensive review of silicon based cross-coupling agents: Denmark, S. E. et al. "Organic Reactions, Volume 75" Denmark, S. E. ed., John Wiley and Sons, 233, 2011