Additional Properties
Hydrolytic Sensitivity 8: reacts rapidly with moisture, water, protic solvents Safety
Hazard Info ihl rat, LCLo: 300 ppm/4H
Packaging Under Nitrogen Tri-substituted Silane Reducing Agent Organosilanes are hydrocarbon-like and possess the ability to serve as both ionic and free-radical reducing agents. These reagents and their reaction by-products are safer and more easily handled and disposed than many other reducing agents. The metallic nature of silicon and its low electronegativity relative to hydrogen lead to polarization of the Si-H bond yielding a hydridic hydrogen and a milder reducing agent compared to aluminum-, boron-, and other metal-based hydrides. A summary of some key silane reductions are presented in Table 1 of the Silicon-Based Reducing Agents brochure. Methyldichlorosilane
; Dichloromethylsilane
Viscosity: 0.60 cSt
ΔHcomb: 163 kJ/mol
ΔHvap: 29.3 kJ/mol
Dipole moment: 1.91 debye
Coefficient of thermal expansion: 1.0 x 10-3
Specific heat: 0.8 J/g/°C
Vapor pressure, 24 °C: 400 mm
Critical temperature: 215-8 °C
Critical pressure: 37.7 atm
Provides better diastereoselective reductive aldol reaction between an aldehyde and an acrylate ester than other silanes
Forms high-boiling polymeric by-products upon aqueous work-up
Extensive review of silicon based reducing agents: Larson, G.; Fry, J. L. "Ionic and Organometallic-Catal
yzed Organosilane Reductions", Wipf, P., Ed.; Wiley, 2007
Gelest, Inc.
Done
Datasheet
Description
Additional Properties
Hydrolytic Sensitivity 8: reacts rapidly with moisture, water, protic solvents Safety
Hazard Info ihl rat, LCLo: 300 ppm/4H
Packaging Under Nitrogen Tri-substituted Silane Reducing Agent Organosilanes are hydrocarbon-like and possess the ability to serve as both ionic and free-radical reducing agents. These reagents and their reaction by-products are safer and more easily handled and disposed than many other reducing agents. The metallic nature of silicon and its low electronegativity relative to hydrogen lead to polarization of the Si-H bond yielding a hydridic hydrogen and a milder reducing agent compared to aluminum-, boron-, and other metal-based hydrides. A summary of some key silane reductions are presented in Table 1 of the Silicon-Based Reducing Agents brochure. Methyldichlorosilane
; Dichloromethylsilane
Viscosity: 0.60 cSt
ΔHcomb: 163 kJ/mol
ΔHvap: 29.3 kJ/mol
Dipole moment: 1.91 debye
Coefficient of thermal expansion: 1.0 x 10-3
Specific heat: 0.8 J/g/°C
Vapor pressure, 24 °C: 400 mm
Critical temperature: 215-8 °C
Critical pressure: 37.7 atm
Provides better diastereoselective reductive aldol reaction between an aldehyde and an acrylate ester than other silanes
Forms high-boiling polymeric by-products upon aqueous work-up
Extensive review of silicon based reducing agents: Larson, G.; Fry, J. L. "Ionic and Organometallic-Catal
yzed Organosilane Reductions", Wipf, P., Ed.; Wiley, 2007
Additional Properties
Hydrolytic Sensitivity 8: reacts rapidly with moisture, water, protic solvents Safety
Hazard Info ihl rat, LCLo: 300 ppm/4H
Packaging Under Nitrogen Tri-substituted Silane Reducing Agent Organosilanes are hydrocarbon-like and possess the ability to serve as both ionic and free-radical reducing agents. These reagents and their reaction by-products are safer and more easily handled and disposed than many other reducing agents. The metallic nature of silicon and its low electronegativity relative to hydrogen lead to polarization of the Si-H bond yielding a hydridic hydrogen and a milder reducing agent compared to aluminum-, boron-, and other metal-based hydrides. A summary of some key silane reductions are presented in Table 1 of the Silicon-Based Reducing Agents brochure. Methyldichlorosilane
; Dichloromethylsilane
Viscosity: 0.60 cSt
ΔHcomb: 163 kJ/mol
ΔHvap: 29.3 kJ/mol
Dipole moment: 1.91 debye
Coefficient of thermal expansion: 1.0 x 10-3
Specific heat: 0.8 J/g/°C
Vapor pressure, 24 °C: 400 mm
Critical temperature: 215-8 °C
Critical pressure: 37.7 atm
Provides better diastereoselective reductive aldol reaction between an aldehyde and an acrylate ester than other silanes
Forms high-boiling polymeric by-products upon aqueous work-up
Extensive review of silicon based reducing agents: Larson, G.; Fry, J. L. "Ionic and Organometallic-Catal
yzed Organosilane Reductions", Wipf, P., Ed.; Wiley, 2007
Packaging Under Nitrogen
Tri-substituted Silane Reducing Agent
Organosilanes are hydrocarbon-like and possess the ability to serve as both ionic and free-radical reducing agents. These reagents and their reaction by-products are safer and more easily handled and disposed than many other reducing agents. The metallic nature of silicon and its low electronegativity relative to hydrogen lead to polarization of the Si-H bond yielding a hydridic hydrogen and a milder reducing agent compared to aluminum-, boron-, and other metal-based hydrides. A summary of some key silane reductions are presented in Table 1 of the Silicon-Based Reducing Agents brochure.
Methyldichlorosilane; Dichloromethylsilane
Viscosity: 0.60 cSt
ΔHcomb: 163 kJ/mol
ΔHvap: 29.3 kJ/mol
Dipole moment: 1.91 debye
Coefficient of thermal expansion: 1.0 x 10-3
Specific heat: 0.8 J/g/°C
Vapor pressure, 24 °C: 400 mm
Critical temperature: 215-8 °C
Critical pressure: 37.7 atm
Provides better diastereoselective reductive aldol reaction between an aldehyde and an acrylate ester than other silanes
Forms high-boiling polymeric by-products upon aqueous work-up
Extensive review of silicon based reducing agents: Larson, G.; Fry, J. L. "Ionic and Organometallic-Catalyzed Organosilane Reductions", Wipf, P., Ed.; Wiley, 2007
