Application
Effects free-radical reductive addition of alkyl halides to olefins with AIBN.1,2 Reduces benzylic chlorides 70 X faster than silyl hydrides.3 Initiates radical cyclization of polyenes.4
Reference
1. Hershberger, J. Tetrahedron Lett. 1986, 26, 6289. 2. Pike, P. et al. Tetrahedron 1988, 44, 6295. 3. Mayr, H. et al. Angew. Chem., Int. Ed. Engl. 1992, 31, 1046. 4. Spino, C. et al. J. Org. Chem. 1999, 64, 5292.
Safety
Packaging Under Nitrogen Germanium-Base Reducing Agent Tri-n-butylgermane; Tributylgermanium hydride
Reduces acid chlorides to aldehydes in presence of Pd(0)
Effects free-radical reductive addition of alkyl halides to olefins
Reduces benzylic chlorides 70x faster than silyl hydrides
Application
Effects free-radical reductive addition of alkyl halides to olefins with AIBN.1,2 Reduces benzylic chlorides 70 X faster than silyl hydrides.3 Initiates radical cyclization of polyenes.4
Reference
1. Hershberger, J. Tetrahedron Lett. 1986, 26, 6289. 2. Pike, P. et al. Tetrahedron 1988, 44, 6295. 3. Mayr, H. et al. Angew. Chem., Int. Ed. Engl. 1992, 31, 1046. 4. Spino, C. et al. J. Org. Chem. 1999, 64, 5292.
Safety
- Packaging Under Nitrogen
Germanium-Base Reducing Agent
Tri-n-butylgermane; Tributylgermanium hydride
- Reduces acid chlorides to aldehydes in presence of Pd(0)
- Effects free-radical reductive addition of alkyl halides to olefins
- Reduces benzylic chlorides 70x faster than silyl hydrides
