Affinity purified Rabbit polyclonal IL21 antibody Background: IL21 is a pleiotropic cytokine produced by CD4+ T cells in response to antigenic stimulation. Its action generally enhances antigen-specific responses of immune cells. The biological effects of IL21 include induction of differentiation of T-cells-stimulated-B
-cells into plasma cells and memory B-cells, stimulation (in conjunction) with IL4 of IgG production, and induction of apoptotic effects in na‹ve B-cells and stimulated B-cells in the absence of T-cell signaling. Additionally, IL21 promotes the anti-tumor activity of CD8+ T-cells and NK cells.
Affinity purified Rabbit polyclonal IL21 antibody
Background:
IL21 is a pleiotropic cytokine produced by CD4+ T cells in response to antigenic stimulation. Its action generally enhances antigen-specific responses of immune cells. The biological effects of IL21 include induction of differentiation of T-cells-stimulated-B-cells into plasma cells and memory B-cells, stimulation (in conjunction) with IL4 of IgG production, and induction of apoptotic effects in na‹ve B-cells and stimulated B-cells in the absence of T-cell signaling. Additionally, IL21 promotes the anti-tumor activity of CD8+ T-cells and NK cells.
