Fitzgerald Industries International, Inc. Synaptotagmin IV antibody 70R-7797

Description
Rabbit polyclonal Human Synaptotagmin IV antibody Background: Synaptotagmin family proteins consist of a single N-terminal transmembrane domain and C-terminal tandem C2 domains (C2A and C2B), which have the ability to bind Ca2+ and phospholipid, and 15 synaptotagmin isoforms have been reported in mice and humans to date. The best characterized isoform, synaptotagmin I, is essential for synaptic vesicle exocytosis and endocytosis. It has been reported that i) synaptotagmin IV expression is regulated by neural activity and that it is thought to be involved in synaptic plasticity, ii) that synaptotagmin IV is present on dense core vesicles in NGF-differentiated PC12 cells and may control their exocytosis, and iii) that synaptotagmin IV regulates glutamate release by astrocytes.
Description
Rabbit polyclonal Human Synaptotagmin IV antibody Background: Synaptotagmin family proteins consist of a single N-terminal transmembrane domain and C-terminal tandem C2 domains (C2A and C2B), which have the ability to bind Ca2+ and phospholipid, and 15 synaptotagmin isoforms have been reported in mice and humans to date. The best characterized isoform, synaptotagmin I, is essential for synaptic vesicle exocytosis and endocytosis. It has been reported that i) synaptotagmin IV expression is regulated by neural activity and that it is thought to be involved in synaptic plasticity, ii) that synaptotagmin IV is present on dense core vesicles in NGF-differentiated PC12 cells and may control their exocytosis, and iii) that synaptotagmin IV regulates glutamate release by astrocytes.

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Fitzgerald Industries International, Inc.
Acton, MA, USA
Synaptotagmin IV antibody
70R-7797
Synaptotagmin IV antibody 70R-7797
Rabbit polyclonal Human Synaptotagmin IV antibody Background: Synaptotagmin family proteins consist of a single N-terminal transmembrane domain and C-terminal tandem C2 domains (C2A and C2B), which have the ability to bind Ca2+ and phospholipid, and 15 synaptotagmin isoforms have been reported in mice and humans to date. The best characterized isoform, synaptotagmin I, is essential for synaptic vesicle exocytosis and endocytosis. It has been reported that i) synaptotagmin IV expression is regulated by neural activity and that it is thought to be involved in synaptic plasticity, ii) that synaptotagmin IV is present on dense core vesicles in NGF-differentiated PC12 cells and may control their exocytosis, and iii) that synaptotagmin IV regulates glutamate release by astrocytes.

Rabbit polyclonal Human Synaptotagmin IV antibody
Background:
Synaptotagmin family proteins consist of a single N-terminal transmembrane domain and C-terminal tandem C2 domains (C2A and C2B), which have the ability to bind Ca2+ and phospholipid, and 15 synaptotagmin isoforms have been reported in mice and humans to date. The best characterized isoform, synaptotagmin I, is essential for synaptic vesicle exocytosis and endocytosis. It has been reported that i) synaptotagmin IV expression is regulated by neural activity and that it is thought to be involved in synaptic plasticity, ii) that synaptotagmin IV is present on dense core vesicles in NGF-differentiated PC12 cells and may control their exocytosis, and iii) that synaptotagmin IV regulates glutamate release by astrocytes.

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Technical Specifications

  Fitzgerald Industries International, Inc.
Product Category Biological Materials
Product Number 70R-7797
Product Name Synaptotagmin IV antibody
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