Fitzgerald Industries International, Inc. HGF beta antibody 70R-7721

Description
Rabbit polyclonal Human HGF beta antibody Background: Hepatocyte Growth factor (HGF) was discovered as a mitogen for hepatocytes. HGF was subsequently found to be identical to the scatter factor, which destroys epithelial cell adhesion and promotes cell movement. Some reports have shown that HGF is expressed in normal and malignant mammary epithelium. HGF has also been reported to promote motility and growth of epithelial cells, to induce morphogenesis of epithelial cells and to promote vascularization. It has been speculated that HGF is involved in the growth and metastasis of cancer cells. The first step in the initiation of HGF action is dependent on its binding to a specific cell surface receptor, the HGF receptor, encoded by the proto-oncogene cMet. It has been suggested that cMet mediates both responses, i.e., promotion of growth and motility of HGF.
Description
Rabbit polyclonal Human HGF beta antibody Background: Hepatocyte Growth factor (HGF) was discovered as a mitogen for hepatocytes. HGF was subsequently found to be identical to the scatter factor, which destroys epithelial cell adhesion and promotes cell movement. Some reports have shown that HGF is expressed in normal and malignant mammary epithelium. HGF has also been reported to promote motility and growth of epithelial cells, to induce morphogenesis of epithelial cells and to promote vascularization. It has been speculated that HGF is involved in the growth and metastasis of cancer cells. The first step in the initiation of HGF action is dependent on its binding to a specific cell surface receptor, the HGF receptor, encoded by the proto-oncogene cMet. It has been suggested that cMet mediates both responses, i.e., promotion of growth and motility of HGF.

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Product
Description
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Fitzgerald Industries International, Inc.
Acton, MA, USA
HGF beta antibody
70R-7721
HGF beta antibody 70R-7721
Rabbit polyclonal Human HGF beta antibody Background: Hepatocyte Growth factor (HGF) was discovered as a mitogen for hepatocytes. HGF was subsequently found to be identical to the scatter factor, which destroys epithelial cell adhesion and promotes cell movement. Some reports have shown that HGF is expressed in normal and malignant mammary epithelium. HGF has also been reported to promote motility and growth of epithelial cells, to induce morphogenesis of epithelial cells and to promote vascularization. It has been speculated that HGF is involved in the growth and metastasis of cancer cells. The first step in the initiation of HGF action is dependent on its binding to a specific cell surface receptor, the HGF receptor, encoded by the proto-oncogene cMet. It has been suggested that cMet mediates both responses, i.e., promotion of growth and motility of HGF.

Rabbit polyclonal Human HGF beta antibody
Background:
Hepatocyte Growth factor (HGF) was discovered as a mitogen for hepatocytes. HGF was subsequently found to be identical to the scatter factor, which destroys epithelial cell adhesion and promotes cell movement. Some reports have shown that HGF is expressed in normal and malignant mammary epithelium. HGF has also been reported to promote motility and growth of epithelial cells, to induce morphogenesis of epithelial cells and to promote vascularization. It has been speculated that HGF is involved in the growth and metastasis of cancer cells. The first step in the initiation of HGF action is dependent on its binding to a specific cell surface receptor, the HGF receptor, encoded by the proto-oncogene cMet. It has been suggested that cMet mediates both responses, i.e., promotion of growth and motility of HGF.

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Technical Specifications

  Fitzgerald Industries International, Inc.
Product Category Biological Materials
Product Number 70R-7721
Product Name HGF beta antibody
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