Fitzgerald Industries International, Inc. Drebrin A antibody 70R-7682

Rabbit polyclonal Human Drebrin A antibody Background: Drebrin (developmentally regulated brain protein), isolated and identified from chicken brain as a protein associated with brain development, is conserved over species, and there are two isoforms, drebrin A and drebrin E in mammals such as rat and human. Drebrin has actin filament-binding activity and has drawn attention as a protein generally involved in biological phenomena related to intracellular actin cytoskeletal-system including cell migration. Drebrin A is present specifically at neuron dendritic spines in the adult brain. Drebrin A is reported to decrease in Alzheimer's disease, Down syndrome and aged brain, and it is suggested that drebrin A is related to decline of cognitive function.