Fitzgerald Industries International, Inc. beta Amyloid antibody 70R-7636

Description
Rabbit polyclonal Human beta Amyloid antibody Background: Alzheimer?s Disease (AD) is characterized by the presence of extracellular plaques and intracellular neurofibrillary tangles(NFTs) in the brain. The major protein component of these plaques is beta amyloid peptide(ABeta), a 40 to 43 amino acid peptide cleaved from amyloid precursor protein by beta-secretase and a putative gamma-secretase. Increased release of the ?longer forms? of ABeta peptide, ABeta42 or ABeta43, which have a greater tendency to aggregate than ABeta40, occurs in individuals expressing certain genetic mutations, expressing certain ApoE alles, and may involve other, still undiscovered, factors, Many researchers theorize that it is this increased release of ABeta42/ABeta43 which leads to the abnormal deposition of ABeta and the associated neurotoxicity in the brains of affected individuals.
Description
Rabbit polyclonal Human beta Amyloid antibody Background: Alzheimer?s Disease (AD) is characterized by the presence of extracellular plaques and intracellular neurofibrillary tangles(NFTs) in the brain. The major protein component of these plaques is beta amyloid peptide(ABeta), a 40 to 43 amino acid peptide cleaved from amyloid precursor protein by beta-secretase and a putative gamma-secretase. Increased release of the ?longer forms? of ABeta peptide, ABeta42 or ABeta43, which have a greater tendency to aggregate than ABeta40, occurs in individuals expressing certain genetic mutations, expressing certain ApoE alles, and may involve other, still undiscovered, factors, Many researchers theorize that it is this increased release of ABeta42/ABeta43 which leads to the abnormal deposition of ABeta and the associated neurotoxicity in the brains of affected individuals.

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Fitzgerald Industries International, Inc.
Acton, MA, USA
beta Amyloid antibody
70R-7636
beta Amyloid antibody 70R-7636
Rabbit polyclonal Human beta Amyloid antibody Background: Alzheimer?s Disease (AD) is characterized by the presence of extracellular plaques and intracellular neurofibrillary tangles(NFTs) in the brain. The major protein component of these plaques is beta amyloid peptide(ABeta), a 40 to 43 amino acid peptide cleaved from amyloid precursor protein by beta-secretase and a putative gamma-secretase. Increased release of the ?longer forms? of ABeta peptide, ABeta42 or ABeta43, which have a greater tendency to aggregate than ABeta40, occurs in individuals expressing certain genetic mutations, expressing certain ApoE alles, and may involve other, still undiscovered, factors, Many researchers theorize that it is this increased release of ABeta42/ABeta43 which leads to the abnormal deposition of ABeta and the associated neurotoxicity in the brains of affected individuals.

Rabbit polyclonal Human beta Amyloid antibody
Background:
Alzheimer?s Disease (AD) is characterized by the presence of extracellular plaques and intracellular neurofibrillary tangles(NFTs) in the brain. The major protein component of these plaques is beta amyloid peptide(ABeta), a 40 to 43 amino acid peptide cleaved from amyloid precursor protein by beta-secretase and a putative gamma-secretase. Increased release of the ?longer forms? of ABeta peptide, ABeta42 or ABeta43, which have a greater tendency to aggregate than ABeta40, occurs in individuals expressing certain genetic mutations, expressing certain ApoE alles, and may involve other, still undiscovered, factors, Many researchers theorize that it is this increased release of ABeta42/ABeta43 which leads to the abnormal deposition of ABeta and the associated neurotoxicity in the brains of affected individuals.

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Technical Specifications

  Fitzgerald Industries International, Inc.
Product Category Biological Materials
Product Number 70R-7636
Product Name beta Amyloid antibody
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