Rabbit affinity purified polyclonal JAK1 antibody Background: JAK1 is a member of a new class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-r
elated domain immediately N-terminal to the PTK domain. The second phosphotransferase domain bears all the hallmarks of a protein kinase, although its structure differs significantly from that of the PTK and threonine/serine kinase family members. JAK1 is a large, widely expressed membrane-associated phosphoprotein. JAK1 is involved in the interferon-alpha/bet
a and -gamma signal transduction pathways.
Rabbit affinity purified polyclonal JAK1 antibody
Background:
JAK1 is a member of a new class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The second phosphotransferase domain bears all the hallmarks of a protein kinase, although its structure differs significantly from that of the PTK and threonine/serine kinase family members. JAK1 is a large, widely expressed membrane-associated phosphoprotein. JAK1 is involved in the interferon-alpha/beta and -gamma signal transduction pathways.
