Fitzgerald Industries International, Inc. RNF178 antibody 70R-6420

Description
Rabbit polyclonal RNF178 antibody Background: MARCH8 is an E3 ubiquitin-protein ligase that may regulate immune responses by promoting ubiquitination of MHC-II and CD86, which leads to their subsequent endocytosis and lysosomal degradation. It may also promote ubiquitination and endocytosis of TFRC and FAS. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugatin g enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
Description
Rabbit polyclonal RNF178 antibody Background: MARCH8 is an E3 ubiquitin-protein ligase that may regulate immune responses by promoting ubiquitination of MHC-II and CD86, which leads to their subsequent endocytosis and lysosomal degradation. It may also promote ubiquitination and endocytosis of TFRC and FAS. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugatin g enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.

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Product
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Fitzgerald Industries International, Inc.
Acton, MA, USA
RNF178 antibody
70R-6420
RNF178 antibody 70R-6420
Rabbit polyclonal RNF178 antibody Background: MARCH8 is an E3 ubiquitin-protein ligase that may regulate immune responses by promoting ubiquitination of MHC-II and CD86, which leads to their subsequent endocytosis and lysosomal degradation. It may also promote ubiquitination and endocytosis of TFRC and FAS. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugatin g enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.

Rabbit polyclonal RNF178 antibody
Background:
MARCH8 is an E3 ubiquitin-protein ligase that may regulate immune responses by promoting ubiquitination of MHC-II and CD86, which leads to their subsequent endocytosis and lysosomal degradation. It may also promote ubiquitination and endocytosis of TFRC and FAS. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.

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Technical Specifications

  Fitzgerald Industries International, Inc.
Product Category Biological Materials
Product Number 70R-6420
Product Name RNF178 antibody
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