Rabbit polyclonal MTHFD2 antibody Background: This protein is a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrof
olate dehydrogenase and methenyltetrahydrofo
late cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD.
Rabbit polyclonal MTHFD2 antibody
Background:
This protein is a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD.