Fitzgerald Industries International, Inc. CHRNA7 Blocking Peptide 33R-9739

Description
A synthetic peptide for use as a blocking control in assays to test for specificity of CHRNA7 antibody, catalog no. 70R-1540 Background: The protein encoded by CHRNA7 displays marked permeability to calcium ions and is a major component of brain nicotinic receptors that are blocked by, and highly sensitive to, alpha-bungarotoxin. Once this receptor binds acetylcholine, it undergoes an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. This gene is located in a region identified as a major susceptibility locus for juvenile myoclonic epilepsy and a chromosomal location involved in the genetic transmission of schizophrenia.
Description
A synthetic peptide for use as a blocking control in assays to test for specificity of CHRNA7 antibody, catalog no. 70R-1540 Background: The protein encoded by CHRNA7 displays marked permeability to calcium ions and is a major component of brain nicotinic receptors that are blocked by, and highly sensitive to, alpha-bungarotoxin. Once this receptor binds acetylcholine, it undergoes an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. This gene is located in a region identified as a major susceptibility locus for juvenile myoclonic epilepsy and a chromosomal location involved in the genetic transmission of schizophrenia.

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Fitzgerald Industries International, Inc.
Acton, MA, USA
CHRNA7 Blocking Peptide
33R-9739
CHRNA7 Blocking Peptide 33R-9739
A synthetic peptide for use as a blocking control in assays to test for specificity of CHRNA7 antibody, catalog no. 70R-1540 Background: The protein encoded by CHRNA7 displays marked permeability to calcium ions and is a major component of brain nicotinic receptors that are blocked by, and highly sensitive to, alpha-bungarotoxin. Once this receptor binds acetylcholine, it undergoes an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. This gene is located in a region identified as a major susceptibility locus for juvenile myoclonic epilepsy and a chromosomal location involved in the genetic transmission of schizophrenia.

A synthetic peptide for use as a blocking control in assays to test for specificity of CHRNA7 antibody, catalog no. 70R-1540
Background:
The protein encoded by CHRNA7 displays marked permeability to calcium ions and is a major component of brain nicotinic receptors that are blocked by, and highly sensitive to, alpha-bungarotoxin. Once this receptor binds acetylcholine, it undergoes an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. This gene is located in a region identified as a major susceptibility locus for juvenile myoclonic epilepsy and a chromosomal location involved in the genetic transmission of schizophrenia.

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Technical Specifications

  Fitzgerald Industries International, Inc.
Product Category Biological Materials
Product Number 33R-9739
Product Name CHRNA7 Blocking Peptide
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