Purified recombinant Human IL17B protein Background: IL17B is a disulfide-linked homodimer of two 161 amino acid polypeptide chains. It belongs to the IL17 family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL17A through IL17F, are secreted as homodimers. IL17B is expressed by T-cells and has been shown to stimulate release of TNF-alpha and IL1beta from cells of the monocyte lineage.
Purified recombinant Human IL17B protein
Background:
IL17B is a disulfide-linked homodimer of two 161 amino acid polypeptide chains. It belongs to the IL17 family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL17A through IL17F, are secreted as homodimers. IL17B is expressed by T-cells and has been shown to stimulate release of TNF-alpha and IL1beta from cells of the monocyte lineage.
