Fitzgerald Industries International, Inc. Bacillus Anthracis (Anthrax) protein (Lethal Antigen) 30R-AA014

Description
Purified recombinant Bacillus Anthracis (Anthrax) protein (Lethal Antigen) Background: One of the three protein components of Anthrax toxin, protective antigen (PA) is the central moiety that mediates the entry of lethal factor and edema factor into the target cell. PA binds to the cell surface via a type I membrane protein with a von Willebrand factor A domain called anthrax toxin receptor. After proteolytic activation to a 63 kDa fragment, PA self-associates to form a heptameric cation-selective, voltage-gated membrane channel.
Description
Purified recombinant Bacillus Anthracis (Anthrax) protein (Lethal Antigen) Background: One of the three protein components of Anthrax toxin, protective antigen (PA) is the central moiety that mediates the entry of lethal factor and edema factor into the target cell. PA binds to the cell surface via a type I membrane protein with a von Willebrand factor A domain called anthrax toxin receptor. After proteolytic activation to a 63 kDa fragment, PA self-associates to form a heptameric cation-selective, voltage-gated membrane channel.

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Fitzgerald Industries International, Inc.
Acton, MA, USA
Bacillus Anthracis (Anthrax) protein (Lethal Antigen)
30R-AA014
Bacillus Anthracis (Anthrax) protein (Lethal Antigen) 30R-AA014
Purified recombinant Bacillus Anthracis (Anthrax) protein (Lethal Antigen) Background: One of the three protein components of Anthrax toxin, protective antigen (PA) is the central moiety that mediates the entry of lethal factor and edema factor into the target cell. PA binds to the cell surface via a type I membrane protein with a von Willebrand factor A domain called anthrax toxin receptor. After proteolytic activation to a 63 kDa fragment, PA self-associates to form a heptameric cation-selective, voltage-gated membrane channel.

Purified recombinant Bacillus Anthracis (Anthrax) protein (Lethal Antigen)
Background:
One of the three protein components of Anthrax toxin, protective antigen (PA) is the central moiety that mediates the entry of lethal factor and edema factor into the target cell. PA binds to the cell surface via a type I membrane protein with a von Willebrand factor A domain called anthrax toxin receptor. After proteolytic activation to a 63 kDa fragment, PA self-associates to form a heptameric cation-selective, voltage-gated membrane channel.

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Technical Specifications

  Fitzgerald Industries International, Inc.
Product Category Biological Materials
Product Number 30R-AA014
Product Name Bacillus Anthracis (Anthrax) protein (Lethal Antigen)
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