Fitzgerald Industries International, Inc. IFN alpha 2a antibody 20R-1002

Polyclonal antibody developed in rabbit against recombinant human interferon alpha 2a produced in plants Background: Interferon alpha 2a (IFN-alpha-2a) belongs to class I interferons. Interferons are produced by the cells of the innate immune system as a part of the defense response to foreign agents such as viruses, parasites and tumor cells. Interferons (class I) bind to a specific cell-surface receptor leading to the transcription and translation of genes coding for proteins having antiviral, antiproliferate and antioncogenic effects, as well as modulating the immune response. IFN-alpha-2a inhibits viral replication within host cells, activates natural killer cells and macrophages and increases antigen presentation to T-lymphocytes. It has been used in the treatment of hepatitis C and various cancers, including leukemia.