Fitzgerald Industries International, Inc. Desmocollin 3 antibody 10R-D103a

Mouse monoclonal Desmocollin 3 antibody Background: Desmocollin-3 is a protein that in humans is encoded by the DSC3 gene. Desmocollin-3 is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The loss of these components leads to a lack of adhesion and a gain of cellular mobility.