Alpha Diagnostic International, Inc. Rat Vanilloid Receptor 1 (VR1) Control/blocking peptide #1 VR11-P

Rat Vanilloid Receptor 1 (VR1) Control/blocking peptide #1 General Information Capsaicin receptor, termed vanilloid receptor subtype 1 (VR1), has been cloned from sensory neurons. VR1 protein is a heat-gated cation channel that exchanges ~10 Ca+ ions for every Na+ ion resulting into neuronal membrane depolarization and elevated int SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Rat Form Antigen/blocking Peptide Antigen 15aa peptide of Rat VR1 Designated (VR11-P or control peptide). Epitope location ~ C-terminus, Cytoplasmic SpCrossreactivity Rat VR11-P control peptide is 93% conserved in guinea pig, mouse, chicken (TRPV1) and 66% conserved in human VR1. It has no significant sequence homology with VRL-1 or TRP or other proteins. Antibody cross-reactivity in various species has not been studied. For research use only, not for diagnostic or therapeutic use.