Alpha Diagnostic International, Inc. Anti-Human Uncoupling Protein 5 (UCP5) IgG #2, aff pure UCP52-A

Anti-Human Uncoupling Protein 5 (UCP5) IgG #2, aff pure General Information Uncoupling proteins (UCP1-5) are a family of mitochondria transport proteins that play a critical role in thermoregulatory heat production and maintenance of basal metabolic rate. BAT is able to dissipate energy as heat via uncoupled mitochondrial respir SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Human SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Affinity purified IgG SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen 16-aa peptide from Human UCP5 (1); Designation (UCP52-P, control peptide) conjugated to KLH; epitope location ~ Cytoplasmic, ~N-terminus SpCrossreactivity UCP5 may be alternatively spliced to produced at least 3 transcripts: UCP5L has a unique 22-aa unique N-terminal sequence; UCP5S is missing 3 aa (23-25 aa) and UCP5S has 31 aa insertion between TM II-IV. The UCP52-P sequence is conserved in all 3 isoforms in rat and mouse UCP5. It is 100% conserved in mouse, rat UCP5/BMCP1. UCP52-P has no appreciable homology with UCP1-4. Antibody crossreactivity of UCP52-S antibodies in various species is not established For research use only, not for diagnostic or therapeutic use.