Alpha Diagnostic International, Inc. Anti-Rat Thyroid Iodide Transporter (TIT) antiserum TIT11-S

Anti-Rat Thyroid Iodide Transporter (TIT) antiserum General Information Iodide (I-) is an essential constituent of thyroid hormones. Thyroid epithelial cells for the biosynthesis of thyroid hormones actively transport it. At the cellular level, Iodide transport is mediated by intrinsic membrane Na+/I+ symporter (NIS/TIT). SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Rat SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Antiserum Unpurified SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen 16-aa peptide from rat TIT (1); Designation (TIT11-P or control peptide/blocking peptide) conjugated to KLH; Epitope location~ C-terminal, Cytoplasmic domain SpCrossreactivity The 16-aa rat TIT11-P peptide sequence is unique to TIT and no significant sequence is seen with glucose transporter or other Na+-dependent transporters. TIT11-P sequence is 100% conserved in mouse, and only 25% in human TIT. Antibody cross-reactivity in various species has not been studied For research use only, not for diagnostic or therapeutic use.