Alpha Diagnostic International, Inc. Anti-Mouse/Human Timeless (Tim1) IgG #1, aff pure TIM11/12-A

Anti-Mouse/Human Timeless (Tim1) IgG #1, aff pure General Information Several endogenous factors have been linked to rhythmicity or circadian behavior of living organisms. In Drosophila, the genes period (dPer) and timeless (tim), and in Neurospora frequency (frq), have been proposed to be responsible for their circadian r SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Human SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Affinity purified IgG SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen A mixture of 14 aa peptide sequence (designated TIM11-P) near the N-terminus of mouse TIM1 and 14 aa peptide sequence (designated TIM12-P), control/blocking peptide) conjugated to KLH; epitope location ~ C-terminus SpCrossreactivity Mouse TIM11-P sequence is 100% conserved in rat Tim1 and 85% homologous with drosophila and human TIM1. Human TIM12-P sequence is 57% homologous with mouse TIM1. Since antibodies have been produced to a mixture of mouse and human TIM1, antibodies should react with mouse, rat, human, and drosophila TIM1. Antibody cross-reactivity with TIM1 from other species is not known For research use only, not for diagnostic or therapeutic use.