Alpha Diagnostic International, Inc. Anti-Rat TNF-alpha Converting Enzyme (TACE), IgG aff. Pure TACE11-A

Anti-Rat TNF-alpha Converting Enzyme (TACE), IgG aff. Pure General Information Recently TACE, a member of the ADAM family (A Disintegrin And Metalloprotease family) protease has been shown to play a central role in a regulated cleavage of human APP. Inhibition of TACE affects both APP secretion and A formation in cultured cells (1 SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Rat SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Affinity purified IgG SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen 17aa peptide of rat TACE; Designated (TACE11-P or control peptide) conjugated to KLH; epitope location ~C-terminus, extracellular domain SpCrossreactivity The rat TACE11-P peptide sequence is 100% conserved in mouse, and 94% in human TACE. No significant sequence homology exists with other proteases. Antibody crossreactivity in various species is not established. For research use only, not for diagnostic or therapeutic use.