Alpha Diagnostic International, Inc. Mouse Synuclein-gamma Control/blocking peptide # 1 SYN14-P

Mouse Synuclein-gamma Control/blocking peptide # 1 General Information The synuclein exists in 3 isoform -syn (chrm 4q21), a 140aa protein, implicated in pathogenesis of PD and related neurodegenerative disorders, it is mainly expressed in brain specifically in neuronal cell bodies and synapses. The 134 aa -syn (chrm 5q35) SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Mouse Form Antigen/blocking Peptide Antigen 18-aa peptide of Rat Gamma SYN1; Designated (SYN14-P or control peptide). conjugated to KLH; epitope location ~ C-terminus SpCrossreactivity The rat SYN14-P peptide sequence is 100% conserved in mouse -synuclein. No significant sequence homology is seen with either human -synuclein or synuclein-alpha or beta) or other proteins. We recommend the use of another antibody for human -synuclein (SYN15-S) that is made using the human sequence. Antibody cross reactivity in various species is not studies For research use only, not for diagnostic or therapeutic use.