Alpha Diagnostic International, Inc. Anti-Rat Synuclein-alpha antiserum # 2 SYN12-S

Anti-Rat Synuclein-alpha antiserum # 2 General Information The synuclein exists in 3 isoform -syn (chrm 4q21), a 140aa protein, implicated in pathogenesis of PD and related neurodegenerative disorders, it is mainly expressed in brain specifically in neuronal cell bodies and synapses. The 134 aa -syn (chrm 5q35) SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Rat SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Antiserum Unpurified SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen 19-aa peptide of Rat SYN1; Designated (SYN12-P or control peptide). conjugated to KLH; epitope location ~ C-terminus SpCrossreactivity The rat SYN12 peptide sequence is only found in rat-synuclein-alpha form 2. Therefore anti-SYN12 will not detect from 1 and 2. It has no appreciable homology with synuclein-beta or other proteins For research use only, not for diagnostic or therapeutic use.