Human Synuclein-alpha Control/blocking peptide #1
General Information
The synuclein exists in 3 isoform -syn (chrm 4q21), a 140aa protein, implicated in pathogenesis of PD and related neurodegenerative disorders, it is mainly expressed in brain specifically in neuronal cell bodies and synapses. The 134 aa -syn (chrm 5q35)
SugApplications
Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization.
SpeciesReactivity
Human
Form
Antigen/blocking Peptide
Antigen
15aa peptide of Human SYN1; Designated (SYN11-P or control peptide). conjugated to KLH; epitope location ~ C-terminus
SpCrossreactivity
The human SYN11 (similar in 140 aa NACP) peptide sequences show 86% homology with mouse/ rat/ chicken SYN-1. No significant homology is seen with beta-synuclein or with other known proteins. The SYN11 antibody cross-reactivity in all species is not known
For research use only, not for diagnostic or therapeutic use.
| Alpha Diagnostic International, Inc. | |
|---|---|
| Product Category | Biological Materials |
| Product Number | SYN11-P |
| Product Name | Human Synuclein-alpha Control/blocking peptide #1 |
