Alpha Diagnostic International, Inc. Anti-Human Synuclein-alpha IgG # 1, aff pure SYN11-A

Anti-Human Synuclein-alpha IgG # 1, aff pure General Information The synuclein exists in 3 isoform -syn (chrm 4q21), a 140aa protein, implicated in pathogenesis of PD and related neurodegenerative disorders, it is mainly expressed in brain specifically in neuronal cell bodies and synapses. The 134 aa -syn (chrm 5q35) SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Human SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Affinity purified IgG SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen 15aa peptide of Human SYN1; Designated (SYN11-P or control peptide). conjugated to KLH; epitope location ~ C-terminus SpCrossreactivity The human SYN11 (similar in 140 aa NACP) peptide sequences show 86% homology with mouse/ rat/ chicken SYN-1. No significant homology is seen with beta-synuclein or with other known proteins. The SYN11 antibody cross-reactivity in all species is not known For research use only, not for diagnostic or therapeutic use.