Alpha Diagnostic International, Inc. Recombinant purified Human Alpha Synuclein (E46K) mutant protein SYN-E46K-R

Recombinant purified Human Alpha Synuclein (E46K) mutant protein General Information The synuclein exists in 3 isoform -syn (chrm 4q21), a 140aa protein, implicated in pathogenesis of PD and related neurodegenerative disorders, it is mainly expressed in brain specifically in neuronal cell bodies and synapses. The 134 aa -syn (chrm 5q35) SpeciesReactivity Human Form Antigen Protein Antigen Human Alpha synuclein recombinant protein (E46K) expressed in E.coli Purity: >95% by SDS-PAGE (Mol.wt 14.45kD). A point mutant (E46K) of the alpha synuclein gene that has been linked to autosomal dominant early onset Parkinson?s disease For research use only, not for diagnostic or therapeutic use.