Alpha Diagnostic International, Inc. Human Alpha Synuclein A30P/A53T Recombinant double mutant protein SYN-A3053T-R

Human Alpha Synuclein A30P/A53T Recombinant double mutant protein General Information The synuclein exists in 3 isoform -syn (chrm 4q21), a 140aa protein, implicated in pathogenesis of PD and related neurodegenerative disorders, it is mainly expressed in brain specifically in neuronal cell bodies and synapses. The 134 aa -syn (chrm 5q35) SpeciesReactivity Human Form Antigen Protein Antigen Human Alpha synuclein recombinant protein expressed in E.coli, a point mutant (A53T) of the alpha synuclein gene that has been linked to autosomal dominant early onset Parkinson?s disease. Purity: >95% by SDS-PAGE (Mol.wt 14.5kD). It is provided in 50 mM Sodium Phosphate buffer, 60 mM NaCl, 17 mM citric acid, pH 6.2 in liquid (100 ug/100 ul) or lyophilized For research use only, not for diagnostic or therapeutic use.