Alpha Diagnostic International, Inc. Anti-human Sclerostin protein, aff pure IgG # 1 SOST11-A

Anti-human Sclerostin protein, aff pure IgG # 1 General Information Sclerostin (213aa in rat and human (chr 17q12) and 211aa in mouse) is a novel secreted osteoclast-derived BMP antagonist with unique ligand specificity; it negatively regulates the formation of bone by repressing the differentiation and/or function of ost SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Human SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Affinity purified IgG SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen 17-aa peptide from Human Sclerostin (1); Designation (SOST11-P, control peptide); epitope location ~ C-terminus SpCrossreactivity The SOST11-P control peptide is 100% conserved in human, 94% to rat and 88% in mouse Sclerostin. Antibody cross-reactivity in various species has not been studied. For research use only, not for diagnostic or therapeutic use.