Alpha Diagnostic International, Inc. Human Sialin control/blocking peptide SIAL11-P

Human Sialin control/blocking peptide General Information Sialic acid storage disease (SASD) are autosomal recessive neurdegenerative disorders that may present as a severa infantile form (ISSD) or a slowly progressive adult form (Salla disease) prevalent in Finland. The patients exccrete large amounts of free SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Human Form Antigen/blocking Peptide Antigen A 17 aa synthetic peptide (designated SIAL11-P; control peptide) was synthesized, conjugated to KLH Epitope location Witin 1st putative extracellualr domain (between 1-2 TM) of human silain SpCrossreactivity The SIAL11-P peptide has no significant sequence with mammalian BNPI/VGLUT1 or other NaPi-related (Type-1 to Type-III) transporters. Sialin from other species has not yet been cloned. Antibody crossreactivity in various species is not established For research use only, not for diagnostic or therapeutic use.