Alpha Diagnostic International, Inc. Anti-Human Sod. Gluc. Transp. 2 (SGLT-2) antiserum # 2 SG24-S

Anti-Human Sod. Gluc. Transp. 2 (SGLT-2) antiserum # 2 General Information SGLT2/SLC5A2 (rat/mouse 670 aa; human 672 aa, chromosome 16p11.2) is the low affinity, high capacity Na+-glucose transporter located in the S1 segments of proximal tubules. It is ~60% identical with SGLT1. SGLT2 mediates saturable Na-dependent and phlo SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Human SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Antiserum Unpurified SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen A 16 AA peptide sequence (designated SG24-P; control peptide) from the C-terminal, cytoplasmic domain 6 of Human SGLT-2 (1) was synthesized, coupled to KLH SpCrossreactivity The Human SG24-P peptide sequence is ~73% conserved in rabbit and 71% in mouse SGLT2. No significant sequence homology exists with other SGLTs. For rat/mouse SGLT2, we recommend the use antibody #1, Cat # SG23-S that is made to the rat SGLT-2 peptide For research use only, not for diagnostic or therapeutic use.