Alpha Diagnostic International, Inc. Human Receptor Activity Modifying Protein 2 (RAMP2) Control/blocking peptide #1 RAMP21-P

Human Receptor Activity Modifying Protein 2 (RAMP2) Control/blocking peptide #1 General Information The calcitonin family peptides probably act through G-protein coupled membrane receptors. The gene for calcitonin receptors has been cloned. It is homologous to GPCRs in family ?B? which typically recognizes regulatory peptides (secretin, glucagons, VIP SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Human Form Antigen/blocking Peptide Antigen A 20-aa peptide from the middle region of human RAMP2 (protein accession #O60895) and A 9-aa peptide of Human RAMP2; the peptide mixture is Designated as (RAMP21-P) or blocking peptide) SpCrossreactivity Human RAMP21-P peptides are 50% and 89% conserved in mouse and rat, 63% in pig RAMP2. However, no significant sequence homology is detected with other RAMPs. Antibody cross-reactivity in various species has not been studied For research use only, not for diagnostic or therapeutic use.