Alpha Diagnostic International, Inc. Human PUMA-alpha (p53-upregulated modulator of apoptosis) control peptide #1 PUMA11-P

Human PUMA-alpha (p53-upregulated modulator of apoptosis) control peptide #1 General Information The p53 tumor antigen is found in increased amounts in a wide variety of transformed cells. The protein is also detectable in many actively proliferating, nontransformed cells, but it is undetectable or present at low levels in resting cells. P53 tumo SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Human Form Antigen/blocking Peptide Antigen 19-aa, Human PUMA (1) Designation (PUMA11-P, control peptide) coupled to KLH Epitope location ~ N-terminus SpCrossreactivity Human PUMA11-P control peptide sequence is not found in alternatively spliced PUMA-beta, gamma or delta. PUMA11-P is 100% conserved in rat & mouse PUMA-alpha. No significant sequence homology is detected with other proteins. Antibody cross-reactivity in various species has not been studied For research use only, not for diagnostic or therapeutic use.