Alpha Diagnostic International, Inc. Mouse Prepro Orexin A Control/blocking peptide #1 PPOX11-P

Mouse Prepro Orexin A Control/blocking peptide #1 General Information Several peptides associated with feeding behavior have been reported recently. Orexins (Orexin-A and Orexin-B) are a family of hypothalamic neuropeptides selectively expressed in the hypothalamus (1-2). Orexin-A and Orexin-B are derived from the same pr SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Mouse Form Antigen/blocking Peptide Antigen 17-aa peptide from mouse prepro-Orexin (1); Designation (# PPOX11-P, control/blocking peptide) conjugated to KLH; epitope location ~ C-terminus SpCrossreactivity Mouse PPOX11-P control peptide shows 82% and 70% identity with rat and human prepro-orexins, respectively. The PPOX11 sequence is not found in Orexin-A and Orexins-B. Therefore, antibodies will not detect mature Orexins A or Orexin-B. Antibody crossreactivity in various species is not established For research use only, not for diagnostic or therapeutic use.