Alpha Diagnostic International, Inc. Anti HIF-prolyl Hydroxylases 1-3 (Pan) IgG, aff pure PHDC12-A

Anti HIF-prolyl Hydroxylases 1-3 (Pan) IgG, aff pure General Information Oxygen is absolutely critical for the survival of mammalian cells. Hypoxia induced factor (HIF) is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. There are 3-types of alpha subunits (HIF1-3alpha) and one HIF-beta su SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Human SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Affinity purified IgG SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen 18-aa peptide of Human PHD2/EGLN1 (1) ; Designated (PHDC12-P or control peptide). This peptide is significantly conserved in PHD1-3 in mouse, rat, and human. epitope location ~ N-terminus SpCrossreactivity Human PHDC12-P was selected to represent a conserved region in PHD1-3 proteins. It is 100% conserved in mouse, rat, and human PHD2/EGLN1. It is 94% conserved in mouse, rat, and human PHD1/EGLN2. Homology with the mouse, rat, and human PHD3/EGLN3 is 88%. The antibodies are expected to recognize PHD1-3 protein from mouse, rat, and human. However, the antibody reactivity needs to be experimentally confirmed For research use only, not for diagnostic or therapeutic use.