Alpha Diagnostic International, Inc. Human Parkin Control/blocking peptide PARK11-P

Human Parkin Control/blocking peptide General Information Parkin is a 465aa (isoforms 1) protein in human (chrm 6q25.2-q27) and mouse, expressed in many tissues, including brain, heart, testis, and skeletal muscle. Parkin isoforms 2 (437-aa) lacks exon 5 (19-206 aa) and the isoforms 3 (316 aa) lacks exons 3-5. SugApplications Control or blocking peptides are recommended for ELISA plate coating for direct ELISA testing of antibodies or competitive ELISA, and antibody blocking or neutralization. SpeciesReactivity Human Form Antigen/blocking Peptide Antigen 23-aa peptide of human PARK isoform 1 Designated (PARK11-P or control peptide). conjugated to KLH; epitope location ~ C-terminus SpCrossreactivity Human PARk11-P peptide sequence is conserved in alternatively spliced isoforms (isoform 1, 465 aa; isoforms 2, 437 aa; and isoform 3, 316 aa;;). It is also highly conserved in mouse and rat (95%), and drosophila?s Parkin (69%). No significant homology of PARK11-P is seen with ubiquitin or any other proteins. Antibody cross-reactivity with Parkin from other species is not known For research use only, not for diagnostic or therapeutic use.