Alpha Diagnostic International, Inc. Purified Recombinant Anthrax Protective Antigen (PA83 kD) protein control for WB PA17-C

Purified Recombinant Anthrax Protective Antigen (PA83 kD) protein control for WB General Information After inhalation by mammals, Bacillus anthracis spores germinate in alveolar macrophages then migrate to lymph nodes where they multiply. The vegetative bacteria excrete the tripartite exotoxin which consists of three polypeptides: protective antigen (PA, SpeciesReactivity Anthrax bacillus Form Protein control Antigen B. Anthracis protective antigen 83 (PA83) was expressed in E. coli and purified. Single major band by SDS-PAGE, Mol wt 83Kda (purity >90-95%). A smaller band, a proteolytic form of PA83, PA63 or PA20 may also appear. For Western blot +ve control (Cat # SpCrossreactivity Rabbit polyclonal antibody (cat # PA17-A) do not cross-react with Lethal Factor (LF) of Bacillus anthracis, Y. Pestis, F. Tularensis and Toxoplasma gondi. The cross-reactivity in various species is not known. Since the epitope of this antibody is locate For research use only, not for diagnostic or therapeutic use.