Alpha Diagnostic International, Inc. Anti-Rat/Human Orexin-A antiserum # 1 OXA11-S

Anti-Rat/Human Orexin-A antiserum # 1 General Information Several peptides associated with feeding behavior have been reported recently. Orexins (Orexin-A and Orexin-B) are a family of hypothalamic neuropeptides selectively expressed in the hypothalamus (1-2). Orexin-A and Orexin-B are derived from the same pr SugApplications Most Antibodies are tested by ELISA and Western. Additional applications, such as IHC or IP may have been tested and will be listed in the product data sheets or published research papers using our products. Typically, antibodies are tested against the SugSecAntibodies http://4adi.com/comm erce/ccc2480-seconda ry-antibodies-rabbit .htm SpeciesReactivity Rat/Human SugNegativeControl Non-immune Rabbit IgG Cat# 20009-1 Form Antiserum Unpurified SugPositiveControl Recombinant or naturally purified proteins or cells of tissues expressing the protein under study can be used as positive controls for Western or IHC. Please review the ?General Information? tan under Product overview section. Control or blocking peptid Antigen 18-aa peptide of mouse Orexin-A (gene accession # 055232) (designated as OXA11-P, control peptide) conjugated to KLH. The peptide has two disulfides (Cys 6-Cys 12 & Cys 7-Cys 14). ; epitope location ~ N-terminus SpCrossreactivity Mouse OXA11-P control peptide is 100% identical in rat, pig, ovine, bovine, dog, human and 81% in chicken. Anti-OXA11 reacts with the full-length (1-33 aa) Orexin-A. The OXA11-P epitope is not found in Orexin-B. Since Orexin-A and Orexin?B are derived from an unprocessed pre-proorexin (130 aa), the anti-Orexin-A antibodies may also react with pre-pro orexin. Antibodies made to prepro-orexin A are also available. Antibody crossreactivity in various species is not established For research use only, not for diagnostic or therapeutic use.